Imputation

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講義前におさらい Genotype imputation for genome-wide association studies. J. Marchini and B. Howie Nature Reviews Genetics 11,499-511 (2010) 方法 IMPUTE v1:HMM IMPUTE v2:IMPUTE v1. + MCMC MACH:like-IMPUTE, parameters (Ne,:unfixed) fastPHAS…