ぱらぱらめくる『Nature Reviews Genetics 2011』10 EWAS(Epigenome-wide association study)

• Epigenome-wide association studies for common human diseases. Vardhman K. Rakyan, Thomas A. Down, David J. Balding & Stephan Beck, p529 | doi:10.1038/nrg3000
• DNAメチル化状態の分類
  • MVP:Methylation variable position
  • DMR:Differentially methlated region
    • iDMR:imprinting-specific
    • tDMR:tissue-specific
    • rDMR:reprogramming-specific
    • cDMR:cancer-specific
    • aDMR:aging-specific
  • ASM:Allele-specific methylation
  • HSM:Haplotype-specific methylation
  • CGIs:CpG islands. 大概の細胞でメチル化されていない
  • CGI shores: CpG islands の岸・縁